TB Research

Drug-Susceptible and Multidrug-Resistant <i>Mycobacterium tuberculosis</i> in a Single Patient

Anthony Baffoe-Bonnie, Eric R. Houpt, Lauren Turner, Denise Dodge, Scott K. Heysell

Emerging infectious diseases · 2019-08

Abstract

A patient who had initial infection with mixed strains of drug-susceptible and multidrug-resistant tuberculosis was presumed to have acquired drug resistance before confirmation that sequential strains were genotypically distinct. Transmitted infection with mixed strains is likely underappreciated; identifying these infections requires spoligotyping and whole-genome sequencing.

MeSH terms

  • Mycobacterium tuberculosis
  • Tuberculosis
  • Multiple drug resistance
  • Drug resistance
  • Drug
  • Virology
  • Biology
  • Extensively drug-resistant tuberculosis
  • Microbiology
  • Whole genome sequencing
  • Genome
  • Medicine