TB Research

Quality of life among HIV-tuberculosis co-infected patients

AnshuKumar Jha, DharmendraKumar Jha, Jyotsna Jha, Basavaprabhu Achappa, Ramesh Holla

Perspectives in Clinical Research · 2019-01

Abstract

BACKGROUND: India is the world's third leading country in terms of people living with human deficiency virus (HIV) (2.1 million) with 0.4 million deaths due to HIV-associated tuberculosis (TB). Physical and mental stress degrades the quality of life (QOL) in these patients. Studies have been done in HIV patients but very few on HIV-TB co-infected patients. Our study aims at assessing and comparing the QOL in HIV patients with and without TB. MATERIALS AND METHODS: It was a cross-sectional study done at Antiretroviral Treatment Center of KMC, Mangalore and District Wenlock Hospital, Mangalore, over 6 months. A sample size was 104. Semi-structured questionnaire to collect clinico-demographic data, World Health Organization QOL (WHOQOL)-HIV BREF to assess the QoL, and Beck's Depression Inventory Scale (Physical health, psychological well-being, social relationship, environmental health, level of independence, and spiritual health) to identify depression were used. The Cronbach's alpha was used to measure the internal consistency for each domain of the WHOQOL-HIV instrument. RESULTS: < 0.05). Internal consistency of each domain was good (α >0.7). CONCLUSION: To improve the QOL in HIV patients, it is important to identify the determinants of QOL and work toward its improvement.

MeSH terms

  • Cronbach's alpha
  • Medicine
  • Quality of life (healthcare)
  • Tuberculosis
  • Human immunodeficiency virus (HIV)
  • Depression (economics)
  • Mental health
  • Beck Depression Inventory
  • Gerontology
  • Psychiatry