TB Research

Tuberculous Osteomyelitis of Frontal Bone: A Case Study and Review of the Literature

Venkateswara Rao Kommu, Rachna Khera, Ravindranath Tagore, Sudha Murthy, Sundaram Challa, Swapna Kotha

Journal of Case Reports · 2019-04

Abstract

Background: Skeletal tuberculosis constitutes about 1% of all tubercular cases. It usually affects the spine and long bones. Tubercular osteomyelitis of skull is a rare entity and therefore diagnosis is not suspected. Skull bones usually involves secondarily from the lung or lymph node focus. Biopsy in these cases confirms the diagnosis. Case Report: A 20 year male patient presented with gradually progressive headache, with multiple episodes of seizures. Magnetic resonance imaging (MRI) brain revealed heterogeneously enhancing extra-axial bi-frontal convexity mass lesion. Histopathology showed necrosis and many caseating as well as non-caseating well defined epithelioid granulomas. Conclusion: A high index of suspicion is important to recognize tuberculous involvement of the skull. Biopsy confirms the diagnosis.

MeSH terms

  • Medicine
  • Caseous necrosis
  • Skull
  • Osteomyelitis
  • Histopathology
  • Biopsy
  • Tuberculosis
  • Radiology
  • Magnetic resonance imaging
  • Lesion
  • Frontal bone
  • Surgery