Same-Day Tools, Including Xpert Ultra and IRISA-TB, for Rapid Diagnosis of Pleural Tuberculosis: a Prospective Observational Study
Richard Meldau, Philippa Randall, Anil Pooran, Jason Limberis, Edson Makambwa, Muhammed Dhansay, Aliasgar Esmail, Keertan Dheda
Journal of Clinical Microbiology · 2019-07
Abstract
The diagnosis of pleural tuberculosis (TB) is problematic. The comparative performance of newer same-day tools for pleural TB, including Xpert MTB/RIF Ultra (ULTRA), has hitherto not been comprehensively studied. Adenosine deaminase (ADA), IRISA-TB (interferon gamma ultrasensitive rapid immunosuspension assay), Xpert MTB/RIF, and ULTRA performance outcomes were evaluated in pleural fluid samples from 149 patients with suspected pleural TB.
MeSH terms
- Medicine
- Tuberculosis
- Adenosine deaminase
- Pleural fluid
- Observational study
- Internal medicine
- Tuberculosis diagnosis
- Virology
- Mycobacterium tuberculosis