Disruption of the SucT acyltransferase in Mycobacterium smegmatis abrogates succinylation of cell envelope polysaccharides
Zuzana Palčeková, Shiva K. Angala, Juan M. Belardinelli, Haig Alexander Eskandarian, Maju Joe, Richard Brunton, Christopher D. Rithner, Victoria Jones, et al. (13 authors)
Journal of Biological Chemistry · 2019-05
Abstract
harboring insertions in the orthologous gene whose ability to microaggregate and form biofilms were altered. Our findings point to an important role of SucT-mediated AG and LAM succinylation in modulating the cell surface properties of mycobacteria.
MeSH terms
- Mycobacterium smegmatis
- Succinylation
- Cell envelope
- Acyltransferase
- Polysaccharide
- Chemistry
- Cell wall
- Biochemistry
- Microbiology
- Cell biology
- Biology