Interferon‐Gamma test for the detection of <i>Mycobacterium tuberculosis</i> complex infection in <i>Macaca mulatta</i> and other non‐human primates
JoAnn L. Yee, Kamm Prongay, Brodie Miles, Jeremy Smedley, Scott G. Hansen, Michael K. Axthelm, Amir Ardeshir, Koen K. A. Van Rompay, et al. (10 authors)
Journal of Medical Primatology · 2019-05
Abstract
We have formatted an assay to detect Mycobacterium tuberculosis complex infections of non-human primates. Commercially available reagents were used to elicit a specific immune response that was measured by interferon-gamma release. Initial evaluation using blood samples from Rhesus macaques experimentally infected with M tuberculosis distinguished infected versus uninfected animals.
MeSH terms
- Mycobacterium tuberculosis
- Tuberculosis
- Immune system
- Interferon gamma
- Biology
- Immunology
- Mycobacterium tuberculosis complex
- Virology
- Gamma interferon
- Interferon
- Interferon γ