TB Research

Genome Sequencing of Polydrug-, Multidrug-, and Extensively Drug-Resistant Mycobacterium tuberculosis Strains from South India

Sivakumar Shanmugam, Narender Kumar, Dina Nair, Mohan Natrajan, Srikanth Tripathy, Sharon J. Peacock, Soumya Swaminathan, Uma Devi Ranganathan

Microbiology Resource Announcements · 2019-03

Abstract

The genomes of 16 clinical Mycobacterium tuberculosis isolates were subjected to whole-genome sequencing to identify mutations related to resistance to one or more anti- Mycobacterium drugs. The sequence data will help in understanding the genomic characteristics of M. tuberculosis isolates and their resistance mutations prevalent in South India.

MeSH terms

  • Mycobacterium tuberculosis
  • Multiple drug resistance
  • Biology
  • Tuberculosis
  • Whole genome sequencing
  • Drug resistance
  • Genome
  • Microbiology
  • Virology
  • Genetics