TREATMENT OF PATIENTS AGAINST THE PULMONARY INVOLVEMENT IN THE CONDITIONS OF COMORBIDITY AT LATE DETECTION OF HIV INFECTION AND WITHOUT ART

Early diagnosis and effective treatment, including operative, in patients with comorbide conditions of pulmonary involvement affected by HIV infection with various infection ways is relevant. Materials and methods. Two clinical cases with pulmonary involvement in comorbidity conditions with the late detection of HIV infection and without antiretroviral therapy are presented. Results. It has been shown that a reduction in the high incidence of adverse outcomes of severe comorbid forms of the disease (in particular, a combination of HIV infection and tuberculosis) can be achieved by conducting an adequate monitoring of these patients, including secondary chemoprophylaxis of tuberculosis as well as, detection, treatment and prevention of co-infections and timely elimination of other possible risk factors (both social and medical). Conclusion. It is necessary to develop optimal algorithms and approaches of medical and psychosocial impact, focused on the initial period of treatment of patients with HIV infection (antiretroviral therapy, anti-tuberculosis therapy, prevention of opportunistic infections, etc.), since it is during this period that the greatest number of severe cases of the disease and adverse outcomes are observed.