Ocular manifestations in tuberculosis cases with HIV in Nepal
Bhatta S, Shah DN, Choudhary M, Thakur A, Pant N
Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH · 2019-07
Abstract
Introduction TB has seen resurgence associated with HIV. Tuberculosis can affect any ocular tissue. The association of HIV with TB is supposed to increase the incidence and plethora of ocular manifestations in tuberculosis. Objectives To study the various ocular manifestations seen in tuberculosis patients with associated HIV infection. Material and methods This hospital based, cross sectional descriptive study was conducted in Tribhuvan University, Teaching Hospital, Maharajgunj, Nepal and Geta Eye Hospital, Kailali from 2010 to 2015. Diagnosed cases of pulmonary and extra pulmonary tuberculosis with HIV co infection were evaluated for ocular manifestations after excluding other opportunistic infections. Results Of 70 cases eligible for the study, extra pulmonary tuberculosis was seen in60% of the cases. 5 patients (7.1 %) had ocular manifestations. CD4 counts were Conclusion This study demonstrated that ocular involvement is a frequent finding in cases with tuberculosis and HIV. Ocular findings are more common in cases with lesser CD4 counts. As ocular tuberculosis can be visually devastating, we recommend regular ocular evaluation of all patients with HIV and systemic tuberculosis.
MeSH terms
- Humans
- Eye Infections, Bacterial
- Tuberculosis, Pulmonary
- AIDS-Related Opportunistic Infections
- Eye Infections, Viral
- HIV Infections
- Cranial Nerve Diseases
- Optic Neuritis
- Retinal Vasculitis
- Choroid Diseases
- Granuloma
- CD4 Lymphocyte Count
- Cross-Sectional Studies
- Immunocompromised Host
- Adolescent
- Adult
- Middle Aged
- Child
- Nepal
- Female
- Male
- Young Adult
- Central Serous Chorioretinopathy