TB Research

Association of adverse drug reaction to anti-tuberculosis medication with quality of life in patients in a tertiary referral hospital

Valadares RMC, Carvalho WDS, Miranda SS

Revista da Sociedade Brasileira de Medicina Tropical · 2019-12

Abstract

Introduction Adverse drug reactions can develop when using anti-tuberculosis medication, and the effects of the drugs can also significantly hinder the treatment of patients. Methods A cross-sectional survey was conducted in 73 patients using two standardized questionnaires and the World Health Organization Quality of Life-Bref. Results All patients reported the presence of adverse drug reactions, 71.6% of which are minor and 28.3% both major and minor. The global quality of life analysis showed that patients with tuberculosis have a good average (67.3%). Conclusions There is an association between quality of life and adverse drug reaction, educational level, and vulnerability.

MeSH terms

  • Humans
  • Tuberculosis
  • Antitubercular Agents
  • Cross-Sectional Studies
  • Quality of Life
  • Socioeconomic Factors
  • Aged
  • Middle Aged
  • Female
  • Male
  • Tertiary Care Centers
  • Drug-Related Side Effects and Adverse Reactions
  • Surveys and Questionnaires