TB Research

A prospective study on the clinical profile and outcome of meningoencephalitis in adults in a South Indian tertiary care centre

Petchiappan V, Pedireddy D, Manickam S, Kuppusamy J

The journal of the Royal College of Physicians of Edinburgh · 2019-12

Abstract

Background Although there are numerous studies on meningitis and encephalitis separately, literature on meningoencephalitis is sparse. In this study we analysed the clinical profile of meningoencephalitis and its clinical outcome. Methods Fifty adults diagnosed with meningoencephalitis from July 2014 to July 2015 in a tertiary care hospital in South India were studied prospectively and their clinical presentation, aetiology and outcome were analysed. Results Among 50 patients, 33 (66%) were male; 39 (78%) were Conclusion Tuberculosis was the most common cause of meningoencephalitis in the studied population, often with subacute presentation, and outcome was good with early institution of antituberculous therapy.

MeSH terms

  • Humans
  • Mycobacterium tuberculosis
  • Meningoencephalitis
  • Neck Pain
  • Fever
  • Anti-Infective Agents
  • Tomography, X-Ray Computed
  • Magnetic Resonance Imaging
  • Prognosis
  • Treatment Outcome
  • Severity of Illness Index
  • Prevalence
  • Risk Assessment
  • Survival Analysis
  • Cohort Studies
  • Prospective Studies
  • Adult
  • Middle Aged
  • India
  • Female
  • Male
  • Young Adult
  • Tertiary Care Centers