Successful treatment of BCG-related immune reconstitution inflammatory syndrome following ex vivo T-cell-depleted haploidentical hematopoietic stem cell transplantation: A case report
Erbey F, Dur AH, Atay D, Akçay A, Tecimer T, Öztürk G
Pediatric transplantation · 2019-05
Abstract
IRIS is a phenomenon describing localized inflammatory reactions at BCG vaccination site and development of lymphadenopathy as immune system recovers. It is a rare entity in children following haploidentical HSCT. We represent the successful treatment of a case with fluctuating lymphadenopathy due to BCG vaccine during immune reconstitution period following ex vivo T-cell-depleted haploidentical HSCT.
MeSH terms
- T-Lymphocytes
- Humans
- Tuberculosis, Lymph Node
- Severe Combined Immunodeficiency
- BCG Vaccine
- Antitubercular Agents
- Lymphocyte Depletion
- Hematopoietic Stem Cell Transplantation
- Infant
- Turkey
- Female
- Immune Reconstitution Inflammatory Syndrome