TB Research

One-Stage Surgical Treatment for Consecutive Multisegment Thoracic Spinal Tuberculosis with Kyphosis by Posterior-Only Debridement, Interbody Fusion, and Instrumentation

Wu W, Li Z, Wang S, Zhang H, Lin R, Lin J

World neurosurgery · 2019-04

Abstract

Objective To evaluate the clinical efficacy and feasibility of one-stage surgical treatment for consecutive multisegment thoracic spinal tuberculosis with kyphosis by posterior-only debridement, interbody fusion, and instrumentation. Methods Sixty-two patients who underwent posterior debridement, interbody fusion, and instrumentation were reviewed for radiographic fusion, region kyphosis, neurologic status, and clinical outcomes. Thoracic Cobb's angle and Frankel grading system were used to assess kyphosis and neurologic improvements, respectively. Operation time, blood loss, erythrocyte sedimentation rate, C-reactive protein, visual analogue scale score, and postoperative complications were recorded to evaluate efficacy and feasibility. Results The surgery duration was 234.5 ± 91.3 minutes, with blood loss of 761.3 ± 598.5 mL. The levels of erythrocyte sedimentation rate and C-reactive protein in all patients decreased gradually to normal within 3 months after the surgery. Kyphosis angle was corrected from 16.9 ± 10.9° preoperatively to 10.4 ± 6.3° postoperatively (P Conclusions One-stage posterior surgery of debridement, interbody fusion and instrumentation could serve as an efficient way to cure patients with consecutive multisegment thoracic spinal tuberculosis.

MeSH terms

  • Thoracic Vertebrae
  • Humans
  • Tuberculosis, Spinal
  • Kyphosis
  • Postoperative Complications
  • C-Reactive Protein
  • Antitubercular Agents
  • Pain Measurement
  • Blood Sedimentation
  • Treatment Outcome
  • Debridement
  • Spinal Fusion
  • Retrospective Studies
  • Adult
  • Aged
  • Aged, 80 and over
  • Middle Aged
  • Female
  • Male
  • Young Adult
  • Operative Time