A Breath of Fresh Air: BCG Prevents Adult Pulmonary Tuberculosis

Objectives The efficacy of childhood BCG vaccination in the prevention of adult pulmonary tuberculosis is not universally accepted. Methods We reviewed the published literature and summarized studies of BCG vaccination reporting long-term protection against pulmonary TB. Results We identified 15 papers reporting prospective studies and their long-term follow up, retrospective studies or systematic reviews. Conclusions Good quality evidence supports the efficacy of BCG vaccination in the prevention of adult pulmonary tuberculosis.