TB Research

Genomic Analysis of Cardiac Surgery-Associated Mycobacterium chimaera Infections, United States

Hasan NA, Epperson LE, Lawsin A, Rodger RR, Perkins KM, Halpin AL, Perry KA, Moulton-Meissner H, et al. (14 authors)

Emerging infectious diseases · 2019-03

Abstract

A surgical heater-cooler unit has been implicated as the source for Mycobacterium chimaera infections among cardiac surgery patients in several countries. We isolated M. chimaera from heater-cooler units and patient infections in the United States. Whole-genome sequencing corroborated a risk for these units acting as a reservoir for this pathogen.

MeSH terms

  • Humans
  • Mycobacterium
  • Mycobacterium Infections
  • Surgical Wound Infection
  • Cardiac Surgical Procedures
  • Genomics
  • Genotype
  • Polymorphism, Single Nucleotide
  • Genome, Bacterial
  • United States