Die another way: Ferroptosis drives tuberculosis pathology
Meunier E, Neyrolles O
The Journal of experimental medicine · 2019-02
Abstract
In this issue of JEM , Amaral et al. (https://doi.org/10.1084/jem.20181776) provide the first evidence that ferroptosis, a newly described form of regulated cell death, is detrimental for the host during a Mycobacterium tuberculosis infection. This finding has important implications for the development of host-directed therapies for tuberculosis.
MeSH terms
- Humans
- Mycobacterium tuberculosis
- Tuberculosis
- Necrosis
- Cell Death
- Ferroptosis