TB Research

Modern Collapse Therapy for Pulmonary Tuberculosis

Krasnov DV, Skluev SV, Petrova YK, Skvortsov DA, Krasnov VA, Felker IG, Grischenko N

Thoracic surgery clinics · 2019-02

Abstract

Multidrug-resistant tuberculosis (TB), extensively drug-resistant TB, and TB-human immunodeficiency virus (HIV) coinfection require a special approach in anti-TB treatment. Most patients cannot be successfully cured by conventional chemotherapy alone. They need a modern approach using minimally invasive therapeutic and surgical techniques. The novel approaches of collapse therapy techniques and minimally invasive osteoplastic thoracoplasty increase the effectiveness of complex anti-TB therapy. Achieving the required selective collapse of lung tissue in destructive pulmonary TB, especially in cases of drug resistance and/or HIV coinfection, leads to bacteriologic conversion, cavity closure, and successful cure.

MeSH terms

  • Lung
  • Humans
  • Tuberculosis, Multidrug-Resistant
  • Tuberculosis, Pulmonary
  • Antitubercular Agents
  • Collapse Therapy
  • Thoracoplasty
  • Adult
  • Female
  • Male
  • Extensively Drug-Resistant Tuberculosis