762. Sex Differences in the Epidemiology of Tuberculosis in Tunisia

Abstract Background According to WHO, many more men than women are diagnosed with tuberculosis (TB) and die from it globally. In light of this fact, examining the gender differences among patients with TB is important to institute effective prevention, coverage and treatment. We aim to study sex differences in the epidemiology and clinical specificities of TB. Methods We conducted a retrospective study of patients with TB, of all ages between January 1995 and December 2016. Data were collected from the regional register of tuberculosis implanted at the anti tuberculosis center ATC of Sfax, Southern Sfax. Results We recorded 2,771 new cases of TB. Sex ratio was 1.2. Pulmonary Tuberculosis (PT) represented 40.5% of all cases of TB (n = 1,121) and was 2.5 times more frequent in men than women (50.3% vs. 28.7%; P Conclusion Our study highlighted sex differences of TB in the region of Sfax with a higher burden and morbidity in men. National TB programs should actively focus in these results with more routine diagnostic and screening. Disclosures All authors: No reported disclosures.