TB Research

The use of bedaquiline to treat patients with multidrug-resistant tuberculosis and end-stage renal disease: A case report

Park S, Lee KM, Kim I, Mok J

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2018-09

Abstract

The use of bedaquiline to treat patients with multidrug-resistant tuberculosis (MDR-TB) and end-stage renal disease (ESRD) may raise safety concerns. Currently, no clinical information is available on the use of bedaquiline to treat MDR-TB patients with ESRD. We report the use of bedaquiline to treat two patients with MDR-TB and ESRD. This report highlights the safety and tolerability of bedaquiline as well as the treatment outcome. The use of bedaquiline in patients with ESRD is also discussed.

MeSH terms

  • Humans
  • Tuberculosis, Multidrug-Resistant
  • Kidney Failure, Chronic
  • Antitubercular Agents
  • Treatment Outcome
  • Middle Aged
  • Male
  • Diarylquinolines