Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report

Rationale Tuberculous meningitis is a highly morbid, often fatal disease. Patient concern We describe a case of an Italian child. DIAGNOSES:: we diagnosed early a Tuberculous meningitis complicated by the occurrence of hydrocephalus, stroke, and paradoxical reaction with brain pseudo-abscesses. Interventions The child started readily a specific therapy associated with steroids and thalidomide was introduced few month later. Outcomes the patient had a favorable outcome without neurologic sequelae. Lessons Despite the prompt specific anti-tubercular and adjuvant corticosteroid therapies, only the addition of thalidomide to the treatment allow to a favorable clinical outcome.