TB Research

Impact of a national nutritional support programme on loss to follow-up after tuberculosis diagnosis in Kenya

Mansour O, Masini EO, Kim BJ, Kamene M, Githiomi MM, Hanson CL

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2018-06

Abstract

Setting Undernourishment is prevalent among tuberculosis (TB) patients. Nutritional support is given to TB patients to prevent and treat undernourishment; it is also used to improve treatment outcomes and as an incentive to keep patients on treatment. Objective To determine whether nutritional support is associated with a reduction in the risk of loss to follow-up (LTFU) among TB patients in Kenya. Design This was a retrospective cohort study using national programmatic data. Records of 362 685 drug-susceptible TB patients from 2012 to 2015 were obtained from Treatment Information from Basic Unit (TIBU), a national case-based electronic data recording system. Patients who were LTFU were compared with those who completed treatment. Results Nutrition counselling was associated with an 8% reduction in the risk of LTFU (RR 0.92, 95%CI 0.89-0.95), vitamins were associated with a 7% reduction (adjusted RR [aRR] 0.93, 95%CI 0.90-0.96) and food support was associated with a 10% reduction (aRR 0.90, 95%CI 0.87-0.94). Among patients who received food support, the addition of nutrition counselling was associated with a 23% reduction in the risk of LTFU (aRR 0.77, 95%CI 0.67-0.88). Conclusion Nutritional support was associated with a reduction in the risk of LTFU. Providing nutrition counselling is important for patients receiving food support.

MeSH terms

  • Humans
  • Tuberculosis
  • Malnutrition
  • Antitubercular Agents
  • Treatment Outcome
  • Nutritional Support
  • Prevalence
  • Risk Factors
  • Retrospective Studies
  • Cohort Studies
  • Follow-Up Studies
  • Adolescent
  • Adult
  • Middle Aged
  • Kenya
  • Female
  • Male
  • Patient Education as Topic
  • Young Adult
  • Lost to Follow-Up