Impact of a national nutritional support programme on loss to follow-up after tuberculosis diagnosis in Kenya
Mansour O, Masini EO, Kim BJ, Kamene M, Githiomi MM, Hanson CL
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2018-06
Abstract
Setting Undernourishment is prevalent among tuberculosis (TB) patients. Nutritional support is given to TB patients to prevent and treat undernourishment; it is also used to improve treatment outcomes and as an incentive to keep patients on treatment. Objective To determine whether nutritional support is associated with a reduction in the risk of loss to follow-up (LTFU) among TB patients in Kenya. Design This was a retrospective cohort study using national programmatic data. Records of 362 685 drug-susceptible TB patients from 2012 to 2015 were obtained from Treatment Information from Basic Unit (TIBU), a national case-based electronic data recording system. Patients who were LTFU were compared with those who completed treatment. Results Nutrition counselling was associated with an 8% reduction in the risk of LTFU (RR 0.92, 95%CI 0.89-0.95), vitamins were associated with a 7% reduction (adjusted RR [aRR] 0.93, 95%CI 0.90-0.96) and food support was associated with a 10% reduction (aRR 0.90, 95%CI 0.87-0.94). Among patients who received food support, the addition of nutrition counselling was associated with a 23% reduction in the risk of LTFU (aRR 0.77, 95%CI 0.67-0.88). Conclusion Nutritional support was associated with a reduction in the risk of LTFU. Providing nutrition counselling is important for patients receiving food support.
MeSH terms
- Humans
- Tuberculosis
- Malnutrition
- Antitubercular Agents
- Treatment Outcome
- Nutritional Support
- Prevalence
- Risk Factors
- Retrospective Studies
- Cohort Studies
- Follow-Up Studies
- Adolescent
- Adult
- Middle Aged
- Kenya
- Female
- Male
- Patient Education as Topic
- Young Adult
- Lost to Follow-Up