Time to Detection in Culture Supports Prediction of Low Transmissibility of Tuberculosis and Discontinuation of Isolation for Low-Risk Patients With A Single AFB-Negative and NAAT-Negative Respiratory Specimen
Khan S, Nakasone A, Ghajar M, Zhowandai M, Prabhu S, Alexander R, Low J, Peterson E, et al. (9 authors)
Infection control and hospital epidemiology · 2018-03
Abstract
For 94 patients with culture-positive pulmonary tuberculosis, time-to-detection (TTD), acid-fast bacilli (AFB) smear, and nucleic acid amplification test (NAAT) results were reviewed. All 12 patients whose first specimen was negative by AFB smear and NAAT had prolonged TTD, indicating low transmissibility and supporting discontinuing isolation for low-risk patients.Infect Control Hosp Epidemiol 2018;39:619-621.
MeSH terms
- Sputum
- Humans
- Mycobacterium tuberculosis
- Tuberculosis, Pulmonary
- Patient Isolation
- Bacteriological Techniques
- Sensitivity and Specificity
- Retrospective Studies
- Nucleic Acid Amplification Techniques
- Databases, Factual
- Academic Medical Centers
- California